The National Institute on Aging (NIA) issues this Funding Opportunity Announcement (FOA) with special review to stimulate interdisciplinary aging-relevant research in the social, affective and economic neurosciences. The NIA invites applications examining social, emotional and economic behaviors of relevance to aging, using approaches that examine mechanisms and processes at both (a) the social, behavioral or psychological (emotional, cognitive, motivational) level, and (b) the neurobiological or genetic level. Applications are encouraged that have an overriding emphasis on economic, social or emotional processes and associated genetic or neurobiological processes. Applications should demonstrate either relevance for aging or for age differences or age-related changes in these processes. Aging-relevant applications can address issues of importance to the well-being and health of either mid-life or older adults, and can include data spanning the entire life course.