Research and Funding

Division of Aging Biology

The objective of DAB-funded research is to elucidate the basic biochemical, genetic, and physiological mechanisms underlying the process of aging and age-related changes in humans and in animal models of human aging. This includes investigations of the gradual or programmed alterations of structure and function that characterize normal aging and investigations of how these adverse changes become risk factors for, or accompany, age-related conditions and disease states. Read more about the Division of Aging Biology »

A parabiosis pairing of a young mouse to an old mouse (see text for explanation)
In a post on January 6, 2015 Dr. Francis Collins commented on research reports by NIA-funded investigators that made Science Magazine’s “Top 10” list for research breakthroughs in 2014. One very important aspect of these recent discoveries on rejuvenation is the potential to improve several aspects of health in concert. Here is a bit more background on the question of rejuvenation and how the discoveries were made.

Interventions Testing Program

The ITP is a cooperative agreement to test compounds for their potential to extend life span using a mouse model. The goal is to provide preliminary data on potential interventions to promote healthy aging in people. Read more about the Interventions Testing Program »

Scientific Resources

Biological and informatics research resources supported by NIA. Read more about scientific resources for aging research »

Nathan Shock Centers

This Core Center Grant program was established in 1995 to enhance well-developed institutional programs in basic research on aging. Read more about the Nathan Shock Centers »

Featured Video

Dr. Nancy Nadon discusses the NIA Interventions Testing Program and how it demonstrates the importance of testing both sexes in studies of aging in animal models.